
Genetic testing may help young Australians find a suitable antidepressant sooner
A recent WA pilot study has found that pharmacogenetic (PGx) testing shows promise as a tool to support antidepressant prescribing...
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Research group
Professor Allan Kermode is an internationally recognised neurologist and clinician-researcher whose work has advanced the understanding, diagnosis and treatment of multiple sclerosis (MS) and related demyelinating diseases. He is Director of the Demyelinating Diseases Centre at the Perron Institute, Clinical Professor of Neurology at The University of Western Australia, and Adjunct Professor of Neuroimmunology at Murdoch University. He also holds an academic appointment at Sun Yat-sen University in China.
Professor Kermode’s foundational research demonstrated that disruption of the blood brain barrier can precede clinical symptoms and other MRI evidence of new MS lesions. This work helped establish magnetic resonance imaging as a critical tool in MS research, clinical monitoring and therapeutic trials. His subsequent research has encompassed disease genetics, neuroimmunology, biomarkers, fatigue and motor function, remyelination, precision medicine and pharmacological treatment.
He established Western Australia’s comprehensive longitudinal database of more than 2,600 people with MS and has led or contributed to numerous international multicentre clinical trials. His current program integrates adaptive trial design, molecular biomarkers, artificial intelligence, transcriptomics and patient centred interventions to improve treatment selection and long term outcomes.
Professor Kermode secured approximately $17 million in competitive funding during the five years to 2026 and has authored or coauthored more than 450 publications. His research has influenced international clinical practice, treatment pathways and government policy, while his mentorship has developed successive generations of neurologists and neuroscience researchers.
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